Sure thing! If you’re starting from Tottenham Court Road, you can hop on the 59 bus—it’ll take you directly to Brixton. You could also take the 159 or the 3, both of which pass through Brixton. The journey usually takes about 30-45 minutes, depending on traffic.
As for tips, Brixton can get pretty busy, especially around the station, so just be prepared for a bit of a crowd when you get there. Other than that, it’s a straightforward trip. Enjoy Brixton—it’s a great area with loads to see and do!